Bradley T R & Metcalf D. The growth of mouse bone marrow cells in vitro. Aust. J. Exp. Biol. Med. Sci. 44:287-300, 1966
نویسنده
چکیده
The article describes the quantitative clonal growth of mouse bone marrow cells in vitro using an agar culture system. Neonatal mouse kidney or whole embryo cells were used as feeder cells to stimulate colony development. The colonies were shown to be composed of large mononuclear cells probably phagocytosing agar and cells typical of the early stages of development of mouse granulocytes. [The SCI® indicates that this paper has been cited over 545 times since 1966.]
منابع مشابه
بررسی اثر داروی ضد سرطانی پومالیدومید بر فعالیت حیاتی و القای آپوپتوز سلولهای تک هسته‌ای مغز استخوان
Background and Objective: Pomalidomide - a combination of Lenalidomide and Thalidomide drugs- is one of the newest anticancer drugs. Pomalidomide induces apoptosis in cancer cells. Furthermore, few studies indicating its relatively low cytotoxic effects on normal peripheral blood cells have been carried out. However, there is yet no information about the effects of Pomalidomide on bone marrow c...
متن کاملالقای سلولهای دندریتیک تولروژن موشی با تنظیم کاهشی ملکول کمک تحریکی CD40 با استفاده از وکتور لنتی ویروس
Induction of Tolerogenic Murine Dendritic Cells by Downregulating the Co-stimulatory Molecule of CD40 Using Lentivirus Vector Mahmoodzadeh A1, Pourfatollah AA1, Karimi MH2, Moazzeni SM1 1Dept. of Immunology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran 2Transplantation Research Center, Nemazee Hospital, Shiraz University of Medical Sciences, Shiraz, Iran. Correspond Aut...
متن کاملبررسی اثر ایزوپرترنول (آگونیست بتا آدرنرژیک) بر تمایز سلولهای بنیادی مزانشیمی مغز استخوان انسان به استئوبلاست در شرایط آزمایشگاهی
Background and Objective: The importance of β-adrenergic signals in bone formation and resorption has been well investigated. However, little is known about the role of β -adrenergic signals in osteoblastic differentiation of mesenchymal stem cells (MSCs), which is critically important in bone physiology and pharmacology. In this study, RUNX2 and Osteocalcin gene expression were quantified in M...
متن کاملبررسی اثر آگونیست -آدرنرژیکی ایزوپروترنول بر بیان miR-886-3p و miR-23a در سلولهای بنیادی مزانشیمی مغز استخوان انسان
Background and Objective: Mobilization of Hematopoietic Stem Cells (HSCs) for transplantation and the importance of -adrenergic signals in induction of this process have been well investigated. However, little is known about the role of -adrenergic signals in mobilization of HSCs and factors influenced by these signals. The Chemokine Stromal Derived Factor -1 (SDF-1) which is expressed by hum...
متن کاملSerum-enzymes during recovery from malnutrition.
5. Law, L. W., Miller, J. H. J. nat. Cancer Inst. 1950, 11, 425. 6. Carnes, W. H., Kaplan, H. S., Brown, M. B., Hirsch, B. B. Cancer Res. 1956, 16, 429. 7. Metcalf, D., Sparrow, N., Nakamura, K., Ishidate, M. Aust. J. exp. Biol. med. Sci. 1961, 39, 441. 8. Auerbach, R. Proc. Nat. Acad. Sci. 1961, 47, 1175. 9. Miller, J. F. A. P. Lancet, 1961, ii, 748. 10. Loutit, J. F. Irradiation of Mice and M...
متن کامل